Experimental cancer drug reverses schizophrenia in adolescent mice
Black mouse in scientist's hand (stock image). Working with mice that mimic the pathological progression of schizophrenia and related disorders, the researchers in this study were able to partially restore disabled neurons so they could connect to other nerve cells.
Source: Johns Hopkins Medicine
Summary:
An experimental anticancer compound appears to have reversed behaviors associated with schizophrenia and restored some lost brain cell function in adolescent mice with a rodent version of the devastating mental illness. The drug is one of a class of compounds known as PAK inhibitors, which have been shown in animal experiments to confer some protection from brain damage due to Fragile X syndrome, an inherited disease in humans marked by mental retardation.enia in adolescent mice
